Which client is safest to recommend for discharge?

When considering the safest client for discharge, the client with asthma exacerbation who has stabilized in the last 12 hours is the most appropriate choice. This client has undergone monitoring and treatment that has effectively managed their symptoms, indicating that their condition is currently stable. The key indicators of safety for discharge in this situation include the resolution of acute symptoms and the ability to maintain stable respiratory function.

The other clients present situations that are less stable or require further monitoring and management. The client on chemotherapy with cellulitis is at risk for complications due to their weakened immune system and ongoing treatment, meaning they need continued supervision and possibly intravenous therapies. The client with diabetes experiencing nausea and vomiting poses a risk for dehydration and potential diabetic complications, warranting continued observation and treatment. Lastly, the client with ulcerative colitis developing a fever may indicate an infection or worsening condition, necessitating further evaluation and possibly more intensive treatment prior to discharge.

Overall, the client with stabilized asthma represents a lower clinical risk and demonstrates a readiness for discharge, making this choice the safest option.